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Traceless native chemical ligation of lipid-modified peptide surfactants by mixed micelle formation

Biology utilizes multiple strategies, including sequestration in lipid vesicles, to raise the rate and specificity of chemical reactions through increases in effective molarity of reactants. We show that micelle-assisted reaction can facilitate native chemical ligations (NCLs) between a peptide-thio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Jin, Shuaijiang, Brea, Roberto J., Rudd, Andrew K., Moon, Stuart P., Pratt, Matthew R., Devaraj, Neal K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7270136/
https://ncbi.nlm.nih.gov/pubmed/32493905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16595-w
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