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Traceless synthesis of ceramides in living cells reveals saturation-dependent apoptotic effects
Mammalian cells synthesize thousands of distinct lipids, yet the function of many of these lipid species is unknown. Ceramides, a class of sphingolipid, are implicated in several cell-signaling pathways but poor cell permeability and lack of selectivity in endogenous synthesis pathways have hampered...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6055205/ https://ncbi.nlm.nih.gov/pubmed/29967152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804266115 |
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