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Traceless native chemical ligation of lipid-modified peptide surfactants by mixed micelle formation

Biology utilizes multiple strategies, including sequestration in lipid vesicles, to raise the rate and specificity of chemical reactions through increases in effective molarity of reactants. We show that micelle-assisted reaction can facilitate native chemical ligations (NCLs) between a peptide-thio...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Jin, Shuaijiang, Brea, Roberto J., Rudd, Andrew K., Moon, Stuart P., Pratt, Matthew R., Devaraj, Neal K.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7270136/
https://ncbi.nlm.nih.gov/pubmed/32493905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16595-w
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