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VapBC22 toxin-antitoxin system from Mycobacterium tuberculosis is required for pathogenesis and modulation of host immune response

Virulence-associated protein B and C toxin-antitoxin (TA) systems are widespread in prokaryotes, but their precise role in physiology is poorly understood. We have functionally characterized the VapBC22 TA system from Mycobacterium tuberculosis. Transcriptome analysis revealed that overexpression of...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Adv
Κύριοι συγγραφείς: Agarwal, Sakshi, Sharma, Arun, Bouzeyen, Rania, Deep, Amar, Sharma, Harsh, Mangalaparthi, Kiran K., Datta, Keshava K., Kidwai, Saqib, Gowda, Harsha, Varadarajan, Raghavan, Sharma, Ravi Datta, Thakur, Krishan Gopal, Singh, Ramandeep
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Association for the Advancement of Science 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269643/
https://ncbi.nlm.nih.gov/pubmed/32537511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba6944
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