VapBC22 toxin-antitoxin system from Mycobacterium tuberculosis is required for pathogenesis and modulation of host immune response

Virulence-associated protein B and C toxin-antitoxin (TA) systems are widespread in prokaryotes, but their precise role in physiology is poorly understood. We have functionally characterized the VapBC22 TA system from Mycobacterium tuberculosis. Transcriptome analysis revealed that overexpression of...

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發表在:Sci Adv
Main Authors: Agarwal, Sakshi, Sharma, Arun, Bouzeyen, Rania, Deep, Amar, Sharma, Harsh, Mangalaparthi, Kiran K., Datta, Keshava K., Kidwai, Saqib, Gowda, Harsha, Varadarajan, Raghavan, Sharma, Ravi Datta, Thakur, Krishan Gopal, Singh, Ramandeep
格式: Artigo
語言:Inglês
出版: American Association for the Advancement of Science 2020
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269643/
https://ncbi.nlm.nih.gov/pubmed/32537511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba6944
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