VapBC22 toxin-antitoxin system from Mycobacterium tuberculosis is required for pathogenesis and modulation of host immune response

Virulence-associated protein B and C toxin-antitoxin (TA) systems are widespread in prokaryotes, but their precise role in physiology is poorly understood. We have functionally characterized the VapBC22 TA system from Mycobacterium tuberculosis. Transcriptome analysis revealed that overexpression of...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Agarwal, Sakshi, Sharma, Arun, Bouzeyen, Rania, Deep, Amar, Sharma, Harsh, Mangalaparthi, Kiran K., Datta, Keshava K., Kidwai, Saqib, Gowda, Harsha, Varadarajan, Raghavan, Sharma, Ravi Datta, Thakur, Krishan Gopal, Singh, Ramandeep
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269643/
https://ncbi.nlm.nih.gov/pubmed/32537511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba6944
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