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Structure and Proposed Activity of a Member of the VapBC Family of Toxin-Antitoxin Systems: VapBC-5 FROM MYCOBACTERIUM TUBERCULOSIS

In prokaryotes, cognate toxin-antitoxin pairs have long been known, but no three-dimensional structure has been available for any given complex from Mycobacterium tuberculosis. Here we report the crystal structure and activity of a member of the VapBC family of complexes from M. tuberculosis. The to...

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Detalhes bibliográficos
Main Authors: Miallau, Linda, Faller, Michael, Chiang, Janet, Arbing, Mark, Guo, Feng, Cascio, Duilio, Eisenberg, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610494/
https://ncbi.nlm.nih.gov/pubmed/18952600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805061200
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