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Preliminary crystallographic analysis of recombinant VapBC-15 toxin–antitoxin complex from Mycobacterium tuberculosis

The Mycobacterium tuberculosis vapBC15 locus encodes a toxin–antitoxin complex. VapC-15 is a toxin and possesses ribonuclease activity and VapB-15 is an antitoxin which both binds and inhibits the VapC-15 toxin. In this study, vapBC15 genes were cloned and co-expressed in Escherichia coli. The compl...

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Библиографические подробности
Главные авторы: Das, Uddipan, Kumar, Nitesh, Gourinath, Samudrala, Srinivasan, Alagiri
Формат: Artigo
Язык:Inglês
Опубликовано: International Union of Crystallography 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818043/
https://ncbi.nlm.nih.gov/pubmed/24192359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113024822
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