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The VapBC1 toxin–antitoxin complex from Mycobacterium tuberculosis: purification, crystallization and X-ray diffraction analysis

Mycobacterium tuberculosis, a major human pathogen, encodes at least 88 toxin–antitoxin (TA) systems. Remarkably, more than half of these modules belong to the VapBC family. Under normal growth conditions, the toxicity of the toxin VapC is neutralized by the protein antitoxin VapB. When bacteria fac...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Principais autores: Lu, Zuokun, Wang, Han, Zhang, Aili, Tan, Yusheng
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909250/
https://ncbi.nlm.nih.gov/pubmed/27303903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16007603
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