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Senescent T cells within suppressive tumor microenvironments: emerging target for tumor immunotherapy
The functional state of the preexisting T cells in the tumor microenvironment is a key determinant for effective antitumor immunity and immunotherapy. Increasing evidence suggests that immunosenescence is an important state of T cell dysfunction that is distinct from exhaustion, a key strategy used...
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| Pubblicato in: | J Clin Invest |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7269563/ https://ncbi.nlm.nih.gov/pubmed/32118585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133679 |
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