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Senescent T cells within suppressive tumor microenvironments: emerging target for tumor immunotherapy

The functional state of the preexisting T cells in the tumor microenvironment is a key determinant for effective antitumor immunity and immunotherapy. Increasing evidence suggests that immunosenescence is an important state of T cell dysfunction that is distinct from exhaustion, a key strategy used...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Liu, Xia, Hoft, Daniel F., Peng, Guangyong
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269563/
https://ncbi.nlm.nih.gov/pubmed/32118585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133679
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