Increased Efficacy of Histone Methyltransferase G9a Inhibitors Against MYCN-Amplified Neuroblastoma

Targeted inhibition of proteins modulating epigenetic changes is an increasingly important priority in cancer therapeutics, and many small molecule inhibitors are currently being developed. In the case of neuroblastoma (NB), a pediatric solid tumor with a paucity of intragenic mutations, epigenetic...

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Bibliografische gegevens
Gepubliceerd in:Front Oncol
Hoofdauteurs: Bellamy, Jacob, Szemes, Marianna, Melegh, Zsombor, Dallosso, Anthony, Kollareddy, Madhu, Catchpoole, Daniel, Malik, Karim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Oncology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269128/
https://ncbi.nlm.nih.gov/pubmed/32537432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00818
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