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Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links
DNA interstrand cross-links (ICLs) are a form of DNA damage that requires the interplay of a number of repair proteins including those of the Fanconi anemia (FA) and the homologous recombination (HR) pathways. Pathogenic variants in the essential gene BRCA2/FANCD1, when monoallelic, predispose to br...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Genes Dev |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Cold Spring Harbor Laboratory Press
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7263144/ https://ncbi.nlm.nih.gov/pubmed/32354836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.336446.120 |
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