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Advances in understanding DNA processing and protection at stalled replication forks

The replisome, the molecular machine dedicated to copying DNA, encounters a variety of obstacles during S phase. Without a proper response to this replication stress, the genome becomes unstable, leading to disease, including cancer. The immediate response is localized to the stalled replisome and i...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Rickman, Kimberly, Smogorzewska, Agata
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446843/
https://ncbi.nlm.nih.gov/pubmed/30670471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201809012
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