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The annealing helicase HARP protects stalled replication forks

Mutations in HepA-related protein (HARP) are the only identified causes of Schimke immunoosseous dysplasia (SIOD). HARP has a unique annealing helicase activity in vitro, but the in vivo functional significance remains unknown. Here, we demonstrated that HARP is recruited to stalled replication fork...

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Hlavní autoři: Yuan, Jingsong, Ghosal, Gargi, Chen, Junjie
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764499/
https://ncbi.nlm.nih.gov/pubmed/19793864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1836409
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