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The annealing helicase HARP protects stalled replication forks
Mutations in HepA-related protein (HARP) are the only identified causes of Schimke immunoosseous dysplasia (SIOD). HARP has a unique annealing helicase activity in vitro, but the in vivo functional significance remains unknown. Here, we demonstrated that HARP is recruited to stalled replication fork...
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Main Authors: | , , |
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Format: | Artigo |
Jezik: | Inglês |
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Cold Spring Harbor Laboratory Press
2009
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764499/ https://ncbi.nlm.nih.gov/pubmed/19793864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1836409 |
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