लोड हो रहा है...
The HARP domain dictates the annealing helicase activity of HARP/SMARCAL1
Mutations in HepA-related protein (HARP, or SMARCAL1) cause Schimke immunoosseous dysplasia (SIOD). HARP has ATP-dependent annealing helicase activity, which helps to stabilize stalled replication forks and facilitate DNA repair during replication. Here, we show that the conserved tandem HARP (2HP)...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128281/ https://ncbi.nlm.nih.gov/pubmed/21525954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.74 |
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