The HARP domain dictates the annealing helicase activity of HARP/SMARCAL1

Mutations in HepA-related protein (HARP, or SMARCAL1) cause Schimke immunoosseous dysplasia (SIOD). HARP has ATP-dependent annealing helicase activity, which helps to stabilize stalled replication forks and facilitate DNA repair during replication. Here, we show that the conserved tandem HARP (2HP)...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Ghosal, Gargi, Yuan, Jingsong, Chen, Junjie
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Scientific Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128281/
https://ncbi.nlm.nih.gov/pubmed/21525954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.74
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars