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SIRT1 directly activates autophagy in human chondrocytes

Osteoarthritis (OA) is the most common form of arthritis worldwide with no effective treatment. Ageing is the primary risk factor for OA. We sought to investigate if there is a distinct and functional convergence of ageing-related mechanisms SIRT1 and autophagy in chondrocytes. Our results show that...

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書目詳細資料
發表在:Cell Death Discov
Main Authors: Sacitharan, Pradeep K., Bou-Gharios, George, Edwards, James R.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260231/
https://ncbi.nlm.nih.gov/pubmed/32528730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0277-0
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