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SIRT1 directly activates autophagy in human chondrocytes

Osteoarthritis (OA) is the most common form of arthritis worldwide with no effective treatment. Ageing is the primary risk factor for OA. We sought to investigate if there is a distinct and functional convergence of ageing-related mechanisms SIRT1 and autophagy in chondrocytes. Our results show that...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cell Death Discov
Päätekijät: Sacitharan, Pradeep K., Bou-Gharios, George, Edwards, James R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260231/
https://ncbi.nlm.nih.gov/pubmed/32528730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0277-0
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