Spermine Oxidase Mediates Helicobacter pylori-induced Gastric Inflammation, DNA Damage, and Carcinogenic Signaling

Helicobacter pylori infection is the main risk factor for development of gastric cancer, the third leading cause of cancer death worldwide. H. pylori colonizes the human gastric mucosa and persists for decades. The inflammatory response is ineffective in clearing the infection, leading to disease pr...

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Gepubliceerd in:Oncogene
Hoofdauteurs: Sierra, Johanna C., Piazuelo, M. Blanca, Luis, Paula B., Barry, Daniel P., Allaman, Margaret M., Asim, Mohammad, Sebrell, Thomas A., Finley, Jordan L., Rose, Kristie L., Hill, Salisha, Holshouser, Steven L., Casero, Robert A., Cleveland, John L., Woster, Patrick M., Schey, Kevin L., Bimczok, Diane, Schneider, Claus, Gobert, Alain P., Wilson, Keith T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260102/
https://ncbi.nlm.nih.gov/pubmed/32350444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1304-6
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