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Increased Expression and Cellular Localization of Spermine Oxidase in Ulcerative Colitis and Relationship to Disease Activity

BACKGROUND: Polyamines are important in cell growth and wound repair, but have also been implicated in inflammation-induced carcinogenesis. Polyamine metabolism includes back-conversion of spermine to spermidine by the enzyme spermine oxidase (SMO), which produces hydrogen peroxide that causes oxida...

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Detalhes bibliográficos
Main Authors: Hong, Shih-Kuang S., Chaturvedi, Rupesh, Blanca Piazuelo, M., Coburn, Lori A., Williams, Christopher S., Delgado, Alberto G., Casero, Robert A., Schwartz, David A., Wilson, Keith T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894261/
https://ncbi.nlm.nih.gov/pubmed/20127992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21224
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