Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection

Polyamines have been implicated in numerous biological processes, including inflammation and carcinogenesis. Homeostatic regulation leads to interconversion of the polyamines putrescine and the downstream metabolites spermidine and spermine. The enzyme spermine oxidase (SMOX), which back-converts sp...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gobert, Alain P., Al-Greene, Nicole T., Singh, Kshipra, Coburn, Lori A., Sierra, Johanna C., Verriere, Thomas G., Luis, Paula B., Schneider, Claus, Asim, Mohammad, Allaman, Margaret M., Barry, Daniel P., Cleveland, John L., Destefano Shields, Christina E., Casero, Robert A., Washington, M. Kay, Piazuelo, M. Blanca, Wilson, Keith T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996034/
https://ncbi.nlm.nih.gov/pubmed/29922289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01242
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