Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection

Polyamines have been implicated in numerous biological processes, including inflammation and carcinogenesis. Homeostatic regulation leads to interconversion of the polyamines putrescine and the downstream metabolites spermidine and spermine. The enzyme spermine oxidase (SMOX), which back-converts sp...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Gobert, Alain P., Al-Greene, Nicole T., Singh, Kshipra, Coburn, Lori A., Sierra, Johanna C., Verriere, Thomas G., Luis, Paula B., Schneider, Claus, Asim, Mohammad, Allaman, Margaret M., Barry, Daniel P., Cleveland, John L., Destefano Shields, Christina E., Casero, Robert A., Washington, M. Kay, Piazuelo, M. Blanca, Wilson, Keith T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996034/
https://ncbi.nlm.nih.gov/pubmed/29922289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01242
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