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Reliable Analysis of Clinical Tumor-Only Whole-Exome Sequencing Data
PURPOSE: Allele-specific copy number alteration (CNA) analysis is essential to study the functional impact of single-nucleotide variants (SNVs) and the process of tumorigenesis. However, controversy over whether it can be performed with sufficient accuracy in data without matched normal profiles and...
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| Publicado no: | JCO Clin Cancer Inform |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Clinical Oncology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7259876/ https://ncbi.nlm.nih.gov/pubmed/32282230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/CCI.19.00130 |
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