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Assessing reliability of intra-tumor heterogeneity estimates from single sample whole exome sequencing data
Tumors are made of evolving and heterogeneous populations of cells which arise from successive appearance and expansion of subclonal populations, following acquisition of mutations conferring them a selective advantage. Those subclonal populations can be sensitive or resistant to different treatment...
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| Publicado no: | PLoS One |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6837753/ https://ncbi.nlm.nih.gov/pubmed/31697689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224143 |
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