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Assessing reliability of intra-tumor heterogeneity estimates from single sample whole exome sequencing data

Tumors are made of evolving and heterogeneous populations of cells which arise from successive appearance and expansion of subclonal populations, following acquisition of mutations conferring them a selective advantage. Those subclonal populations can be sensitive or resistant to different treatment...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Abécassis, Judith, Hamy, Anne-Sophie, Laurent, Cécile, Sadacca, Benjamin, Bonsang-Kitzis, Hélène, Reyal, Fabien, Vert, Jean-Philippe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6837753/
https://ncbi.nlm.nih.gov/pubmed/31697689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224143
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