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Humanized tau antibodies promote tau uptake by human microglia without any increase of inflammation
Immunotherapies targeting pathological tau have recently emerged as a promising approach for treatment of neurodegenerative disorders. We have previously showed that the mouse antibody DC8E8 discriminates between healthy and pathological tau, reduces tau pathology in murine tauopathy models and inhi...
Shranjeno v:
| izdano v: | Acta Neuropathol Commun |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7257136/ https://ncbi.nlm.nih.gov/pubmed/32471486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00948-z |
| Oznake: |
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