Humanized tau antibodies promote tau uptake by human microglia without any increase of inflammation

Immunotherapies targeting pathological tau have recently emerged as a promising approach for treatment of neurodegenerative disorders. We have previously showed that the mouse antibody DC8E8 discriminates between healthy and pathological tau, reduces tau pathology in murine tauopathy models and inhi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Acta Neuropathol Commun
Hauptverfasser: Zilkova, Monika, Nolle, Anna, Kovacech, Branislav, Kontsekova, Eva, Weisova, Petronela, Filipcik, Peter, Skrabana, Rostislav, Prcina, Michal, Hromadka, Tomas, Cehlar, Ondrej, Rolkova, Gabriela Paulikova, Maderova, Denisa, Novak, Michal, Zilka, Norbert, Hoozemans, Jeroen J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257136/
https://ncbi.nlm.nih.gov/pubmed/32471486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00948-z
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge