Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease

BACKGROUND: Numerous epidemiological studies demonstrate that genetic background modifies the onset and the progression of Alzheimer's disease and related neurodegenerative disorders. The efficacious influence of genetic background on the disease pathway of amyloid beta has been meticulously de...

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Bibliografiske detaljer
Main Authors: Stozicka, Zuzana, Zilka, Norbert, Novak, Petr, Kovacech, Branislav, Bugos, Ondrej, Novak, Michal
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958906/
https://ncbi.nlm.nih.gov/pubmed/20937161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-64
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