Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease

BACKGROUND: Numerous epidemiological studies demonstrate that genetic background modifies the onset and the progression of Alzheimer's disease and related neurodegenerative disorders. The efficacious influence of genetic background on the disease pathway of amyloid beta has been meticulously de...

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Main Authors: Stozicka, Zuzana, Zilka, Norbert, Novak, Petr, Kovacech, Branislav, Bugos, Ondrej, Novak, Michal
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958906/
https://ncbi.nlm.nih.gov/pubmed/20937161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-64
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