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Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways

Neurodegeneration, induced by misfolded tau protein, and neuroinflammation, driven by glial cells, represent the salient features of Alzheimer's disease (AD) and related human tauopathies. While tau neurodegeneration significantly correlates with disease progression, brain inflammation seems to...

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Библиографические подробности
Главные авторы: Zilka, Norbert, Kazmerova, Zuzana, Jadhav, Santosh, Neradil, Peter, Madari, Aladar, Obetkova, Dominika, Bugos, Ondrej, Novak, Michal
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334709/
https://ncbi.nlm.nih.gov/pubmed/22397366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-47
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