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Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways

Neurodegeneration, induced by misfolded tau protein, and neuroinflammation, driven by glial cells, represent the salient features of Alzheimer's disease (AD) and related human tauopathies. While tau neurodegeneration significantly correlates with disease progression, brain inflammation seems to...

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Detalhes bibliográficos
Main Authors: Zilka, Norbert, Kazmerova, Zuzana, Jadhav, Santosh, Neradil, Peter, Madari, Aladar, Obetkova, Dominika, Bugos, Ondrej, Novak, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334709/
https://ncbi.nlm.nih.gov/pubmed/22397366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-47
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