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Assessing the origin of high-grade serous ovarian cancer using CRISPR-modification of mouse organoids
High-grade serous ovarian cancer (HG-SOC)—often referred to as a “silent killer”—is the most lethal gynecological malignancy. The fallopian tube (murine oviduct) and ovarian surface epithelium (OSE) are considered the main candidate tissues of origin of this cancer. However, the relative contributio...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7253462/ https://ncbi.nlm.nih.gov/pubmed/32461556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16432-0 |
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