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Patient-derived organoids and high grade serous ovarian cancer: from disease modeling to personalized medicine

BACKGROUND: High grade serous ovarian cancer (HGSOC) is among the deadliest human cancers and its prognosis remains extremely poor. Tumor heterogeneity and rapid acquisition of resistance to conventional chemotherapeutic approaches strongly contribute to poor outcome of patients. The clinical landsc...

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Опубликовано в: :J Exp Clin Cancer Res
Главные авторы: Nero, Camilla, Vizzielli, Giuseppe, Lorusso, Domenica, Cesari, Eleonora, Daniele, Gennaro, Loverro, Matteo, Scambia, Giovanni, Sette, Claudio
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011220/
https://ncbi.nlm.nih.gov/pubmed/33789687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01917-7
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