Mouse and human urothelial cancer organoids: A tool for bladder cancer research

Bladder cancer is a common malignancy that has a relatively poor outcome. Lack of culture models for the bladder epithelium (urothelium) hampers the development of new therapeutics. Here we present a long-term culture system of the normal mouse urothelium and an efficient culture system of human bla...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Mullenders, Jasper, de Jongh, Evelien, Brousali, Anneta, Roosen, Mieke, Blom, Jan P. A., Begthel, Harry, Korving, Jeroen, Jonges, Trudy, Kranenburg, Onno, Meijer, Richard, Clevers, Hans C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410883/
https://ncbi.nlm.nih.gov/pubmed/30787188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803595116
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