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Xenograft and organoid model systems in cancer research

Patient‐derived tumour xenografts and tumour organoids have become important preclinical model systems for cancer research. Both models maintain key features from their parental tumours, such as genetic and phenotypic heterogeneity, which allows them to be used for a wide spectrum of applications. I...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Bleijs, Margit, van de Wetering, Marc, Clevers, Hans, Drost, Jarno
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670015/
https://ncbi.nlm.nih.gov/pubmed/31282586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101654
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