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Xenograft and organoid model systems in cancer research

Patient‐derived tumour xenografts and tumour organoids have become important preclinical model systems for cancer research. Both models maintain key features from their parental tumours, such as genetic and phenotypic heterogeneity, which allows them to be used for a wide spectrum of applications. I...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Bleijs, Margit, van de Wetering, Marc, Clevers, Hans, Drost, Jarno
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670015/
https://ncbi.nlm.nih.gov/pubmed/31282586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101654
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