Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer

Weight loss and anorexia are common symptoms in cancer patients that occur prior to initiation of cancer therapy. Inflammation in the brain is a driver of these symptoms, yet cellular sources of neuroinflammation during malignancy are unknown. In a mouse model of pancreatic ductal adenocarcinoma (PD...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Burfeind, Kevin G, Zhu, Xinxia, Norgard, Mason A, Levasseur, Peter R, Huisman, Christian, Buenafe, Abigail C, Olson, Brennan, Michaelis, Katherine A, Torres, Eileen RS, Jeng, Sophia, McWeeney, Shannon, Raber, Jacob, Marks, Daniel L
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
Fag:
Immunology and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253193/
https://ncbi.nlm.nih.gov/pubmed/32391790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54095
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