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TRIF is a key inflammatory mediator of acute sickness behavior and cancer cachexia

Hypothalamic inflammation is a key component of acute sickness behavior and cachexia, yet mechanisms of inflammatory signaling in the central nervous system remain unclear. Previous work from our lab and others showed that while MyD88 is an important inflammatory signaling pathway for sickness behav...

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Bibliographic Details
Published in:Brain Behav Immun
Main Authors: Burfeind, Kevin G., Zhu, Xinxia, Levasseur, Peter R., Michaelis, Katherine A., Norgard, Mason A., Marks, Daniel L.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129432/
https://ncbi.nlm.nih.gov/pubmed/29852290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2018.05.021
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