Microglia in the hypothalamus respond to tumor‐derived factors and are protective against cachexia during pancreatic cancer

Microglia in the mediobasal hypothalamus (MBH) respond to inflammatory stimuli and metabolic perturbations to mediate body composition. This concept is well studied in the context of high fat diet induced obesity (HFDO), yet has not been investigated in the context of cachexia, a devastating metabol...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Burfeind, Kevin G., Zhu, Xinxia, Norgard, Mason A., Levasseur, Peter R., Huisman, Christian, Michaelis, Katherine A., Olson, Brennan, Marks, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205589/
https://ncbi.nlm.nih.gov/pubmed/32039522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23796
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