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Microglia in the hypothalamus respond to tumor‐derived factors and are protective against cachexia during pancreatic cancer

Microglia in the mediobasal hypothalamus (MBH) respond to inflammatory stimuli and metabolic perturbations to mediate body composition. This concept is well studied in the context of high fat diet induced obesity (HFDO), yet has not been investigated in the context of cachexia, a devastating metabol...

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Bibliografske podrobnosti
izdano v:Glia
Main Authors: Burfeind, Kevin G., Zhu, Xinxia, Norgard, Mason A., Levasseur, Peter R., Huisman, Christian, Michaelis, Katherine A., Olson, Brennan, Marks, Daniel L.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205589/
https://ncbi.nlm.nih.gov/pubmed/32039522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23796
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