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Microglia in the hypothalamus respond to tumor‐derived factors and are protective against cachexia during pancreatic cancer

Microglia in the mediobasal hypothalamus (MBH) respond to inflammatory stimuli and metabolic perturbations to mediate body composition. This concept is well studied in the context of high fat diet induced obesity (HFDO), yet has not been investigated in the context of cachexia, a devastating metabol...

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Dettagli Bibliografici
Pubblicato in:Glia
Autori principali: Burfeind, Kevin G., Zhu, Xinxia, Norgard, Mason A., Levasseur, Peter R., Huisman, Christian, Michaelis, Katherine A., Olson, Brennan, Marks, Daniel L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205589/
https://ncbi.nlm.nih.gov/pubmed/32039522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23796
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