Fine tuning of the unfolded protein response by ISRIB improves neuronal survival in a model of amyotrophic lateral sclerosis

Loss of protein folding homeostasis features many of the most prevalent neurodegenerative disorders. As coping mechanism to folding stress within the endoplasmic reticulum (ER), the unfolded protein response (UPR) comprises a set of signaling mechanisms that initiate a gene expression program to res...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Bugallo, Ricardo, Marlin, Elías, Baltanás, Ana, Toledo, Estefanía, Ferrero, Roberto, Vinueza-Gavilanes, Rodrigo, Larrea, Laura, Arrasate, Montserrat, Aragón, Tomás
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250913/
https://ncbi.nlm.nih.gov/pubmed/32457286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2601-2
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge