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Fine tuning of the Unfolded Protein Response: Assembling the IRE1α interactome

Endoplasmic reticulum (ER) stress is a hallmark feature of secretory cells and many diseases including cancer, neurodegeneration, and diabetes. Adaptation to protein folding stress is mediated by the activation of an integrated signal transduction pathway known as the unfolded protein response (UPR)...

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Detalhes bibliográficos
Main Authors: Hetz, Claudio, Glimcher, Laurie H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101568/
https://ncbi.nlm.nih.gov/pubmed/19748352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.08.021
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