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PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response

The endoplasmic reticulum (ER) responds to changes in intracellular homeostasis through activation of the unfolded protein response (UPR). UPR can facilitate the restoration of cellular homeostasis, via the concerted activation of three ER stress sensors, namely IRE1, PERK and ATF6. Global approache...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gupta, Ananya, Hossain, Muhammad Mosaraf, Read, Danielle E., Hetz, Claudio, Samali, Afshin, Gupta, Sanjeev
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682135/
https://ncbi.nlm.nih.gov/pubmed/26674075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18304
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