PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response

The endoplasmic reticulum (ER) responds to changes in intracellular homeostasis through activation of the unfolded protein response (UPR). UPR can facilitate the restoration of cellular homeostasis, via the concerted activation of three ER stress sensors, namely IRE1, PERK and ATF6. Global approache...

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Pubblicato in:Sci Rep
Autori principali: Gupta, Ananya, Hossain, Muhammad Mosaraf, Read, Danielle E., Hetz, Claudio, Samali, Afshin, Gupta, Sanjeev
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682135/
https://ncbi.nlm.nih.gov/pubmed/26674075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18304
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