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Downregulation of miR-17-92 Cluster by PERK Fine-Tunes Unfolded Protein Response Mediated Apoptosis

An important event in the unfolded protein response (UPR) is activation of the endoplasmic reticulum (ER) kinase PERK. The PERK signalling branch initially mediates a prosurvival response, which progresses to a proapoptotic response upon prolonged ER stress. However, the molecular mechanisms of PERK...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Life (Basel)
Egile Nagusiak: Read, Danielle E., Gupta, Ananya, Cawley, Karen, Fontana, Laura, Agostinis, Patrizia, Samali, Afshin, Gupta, Sanjeev
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7825066/
https://ncbi.nlm.nih.gov/pubmed/33418948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life11010030
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