BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

Both autophagy and apoptosis are tightly regulated processes playing a central role in tissue homeostasis. Bax inhibitor 1 (BI-1) is a highly conserved protein with a dual role in apoptosis and endoplasmic reticulum (ER) stress signalling through the regulation of the ER stress sensor inositol requi...

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Detalhes bibliográficos
Main Authors: Castillo, Karen, Rojas-Rivera, Diego, Lisbona, Fernanda, Caballero, Benjamín, Nassif, Melissa, Court, Felipe A, Schuck, Sebastian, Ibar, Consuelo, Walter, Peter, Sierralta, Jimena, Glavic, Alvaro, Hetz, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230375/
https://ncbi.nlm.nih.gov/pubmed/21926971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.318
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