BAX Inhibitor-1 is a negative regulator of the ER stress sensor IRE1α

Adaptation to endoplasmic reticulum (ER) stress depends on the activation of an integrated signal transduction pathway known as the unfolded protein response (UPR). Bax inhibitor-1 (BI-1) is an evolutionarily conserved ER-resident protein that suppresses cell death. Here we have investigated the rol...

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Detalhes bibliográficos
Main Authors: Lisbona, Fernanda, Rojas-Rivera, Diego, Thielen, Peter, Zamorano, Sebastian, Todd, Derrick, Martinon, Fabio, Glavic, Alvaro, Kress, Christina, Lin, Jonathan H., Walter, Peter, Reed, John C., Glimcher, Laurie H., Hetz, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818874/
https://ncbi.nlm.nih.gov/pubmed/19328063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.02.017
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