BAX Inhibitor-1 is a negative regulator of the ER stress sensor IRE1α

Adaptation to endoplasmic reticulum (ER) stress depends on the activation of an integrated signal transduction pathway known as the unfolded protein response (UPR). Bax inhibitor-1 (BI-1) is an evolutionarily conserved ER-resident protein that suppresses cell death. Here we have investigated the rol...

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Main Authors: Lisbona, Fernanda, Rojas-Rivera, Diego, Thielen, Peter, Zamorano, Sebastian, Todd, Derrick, Martinon, Fabio, Glavic, Alvaro, Kress, Christina, Lin, Jonathan H., Walter, Peter, Reed, John C., Glimcher, Laurie H., Hetz, Claudio
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818874/
https://ncbi.nlm.nih.gov/pubmed/19328063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.02.017
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