Biochemical/Cellular Characterization and Inhibitor discovery of Pseudomonas aeruginosa 15-Lipoxygenase

Pseudomonas aeruginosa is an opportunistic pathogen which can causes nosocomial and chronic infections in immunocompromised patients. P. aeruginosa secretes a lipoxygenase, LoxA, but the biological role of this enzyme is currently unknown. LoxA has poor sequence similarity to both soybean LOX-1 (s15...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Deschamps, Joshua D., Ogunsola, Abiola F., Jameson, J. Brian, Yasgar, Adam, Flitter, Becca A., Freedman, Cody J., Melvin, Jeffrey A., Nguyen, Jason V.M.H., Maloney, David J., Jadhav, Ajit, Simeonov, Anton, Bomberger, Jennifer M., Holman, Theodore R.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249612/
https://ncbi.nlm.nih.gov/pubmed/27226387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00338
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