Increased cerebrospinal fluid amyloid-β during sleep deprivation in healthy middle-aged adults is not due to stress or circadian disruption

BACKGROUND: Concentrations of soluble amyloid-β oscillate with the sleep-wake cycle in the interstitial fluid of mice and cerebrospinal fluid of humans. Further, the concentration of amyloid-β in cerebrospinal fluid increases during sleep deprivation. Stress and disruption of the circadian clock are...

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Xehetasun bibliografikoak
Argitaratua izan da:J Alzheimers Dis
Egile Nagusiak: Blattner, Margaret S., Panigrahi, Sunil K., Toedebusch, Cristina D., Hicks, Terry J., McLeland, Jennifer S., Banks, Ian R., Schaibley, Claire, Ovod, Vitaliy, Mawuenyega, Kwasi G., Bateman, Randall J., Wardlaw, Sharon L., Lucey, Brendan P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246155/
https://ncbi.nlm.nih.gov/pubmed/32250301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-191122
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