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Sleep deprivation affects tau phosphorylation in human cerebrospinal fluid
Tau hyperphosphorylation is an early step in tau-mediated neurodegeneration and is associated with intracellular aggregation of tau as neurofibrillary tangles, neuronal and synaptic loss, and eventual cognitive dysfunction in Alzheimer’s disease. Sleep loss increases the cerebrospinal fluid concentr...
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| Pubblicato in: | Ann Neurol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7289061/ https://ncbi.nlm.nih.gov/pubmed/32057125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25702 |
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