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Tau Phosphorylation Pathway Genes and Cerebrospinal Fluid Tau Levels in Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by the presence in the brain of amyloid plaques, consisting predominately of the amyloid β peptide (Aβ), and neurofibrillary tangles, consisting primarily of tau. Hyper-phosphorylated-tau (p-tau) contributes to neuronal damage, and both p-tau and total-tau (...

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Autores principales: Bekris, Lynn M., Millard, Steve, Lutz, Franziska, Li, Gail, Galasko, Doug R., Farlow, Martin R., Quinn, Joseph F., Kaye, Jeffrey A., Leverenz, James B., Tsuang, Debby W., Yu, Chang-En, Peskind, Elaine R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626266/
https://ncbi.nlm.nih.gov/pubmed/22927204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32094
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