Cerebrospinal Fluid Concentration of Brain-Derived Neurotrophic Factor and Cognitive Function in Non-Demented Subjects

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is an activity-dependent secreted protein that is critical to organization of neuronal networks and synaptic plasticity, especially in the hippocampus. We tested hypothesis that reduced CSF BDNF is associated with age-related cognitive decline. ME...

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Detalhes bibliográficos
Main Authors: Li, Ge, Peskind, Elaine R., Millard, Steven P., Chi, Peter, Sokal, Izabela, Yu, Chang-En, Bekris, Lynn M., Raskind, Murray A., Galasko, Douglas R., Montine, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671606/
https://ncbi.nlm.nih.gov/pubmed/19412541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005424
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